For Research on Diabetic Complications & For Accurate Quantification of Sorbitol
Sorbitol Dehydrogenase is an essential enzyme involved in polyol metabolism. Sorbitol Dehydrogenase, isolated from microorganisms, is characterized by its high substrate specificity and it degrades D-sorbitol, used as a substrate, into fructose. It is believed that diabetic complications are caused by sorbitol accumulation. The conventional enzymes on the market react with sugars other than sorbitol; however, Sorbitol Dehydrogenase with high substrate specificity enables accurate quantification of sorbitol.
When reacted with typical sugars as substrates including glucose, mannitol, and galactose (at 0.5 mol/L concentration) independently or in a mixture, the absorbance did not change, proving high substrate specificity of Sorbitol Dehydrogenase. Sorbitol Dehydrogenase is useful not only in research aggravation mechanism of complications but also in sorbitol quantification in foods.
Activity: 40 - 60units/vial
Molecular Weight 68kDa
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