注册 登录  
 加关注
   显示下一条  |  关闭
温馨提示!由于新浪微博认证机制调整,您的新浪微博帐号绑定已过期,请重新绑定!立即重新绑定新浪微博》  |  关闭

Jackson二抗授权|蛋白|细胞因子

西宝生物科研试剂团队服务糖,寡糖,多糖及检测服务和原料供应。Jackson二抗

 
 
 

日志

 
 
关于我

R&D Systems公司细胞生物学,提供优质的蛋白质,抗体,ELISA试剂盒,实验室试剂,细胞因子.包括Novus Biologicals, BiosPacific, Tocris Bioscience, Boston Biochem和Bionostics. Jackson二抗中国授权代理

网易考拉推荐

山梨醇脱氢酶、醛糖还原酶  

2007-06-25 08:54:37|  分类: 生物化学试剂 |  标签: |举报 |字号 订阅

  下载LOFTER 我的照片书  |
Sorbitol Dehydrogenase, from Microorganism      199-12391    50 units
Wako和光纯药——021-50272975,76,77,78转 6220
Grade: for Biochemistry
Regulation / Hazardous:
Storage condition: Keep at -20 degrees C.
Summary
This product is for research use only. Do not administer it to human.

For Research on Diabetic Complications & For Accurate Quantification of Sorbitol
Sorbitol Dehydrogenase is an essential enzyme involved in polyol metabolism. Sorbitol Dehydrogenase, isolated from microorganisms, is characterized by its high substrate specificity and it degrades D-sorbitol, used as a substrate, into fructose. It is believed that diabetic complications are caused by sorbitol accumulation. The conventional enzymes on the market react with sugars other than sorbitol; however, Sorbitol Dehydrogenase with high substrate specificity enables accurate quantification of sorbitol.

When reacted with typical sugars as substrates including glucose, mannitol, and galactose (at 0.5 mol/L concentration) independently or in a mixture, the absorbance did not change, proving high substrate specificity of Sorbitol Dehydrogenase. Sorbitol Dehydrogenase is useful not only in research aggravation mechanism of complications but also in sorbitol quantification in foods.



醛糖还原酶Aldose Reductase, recombinant
Wako和光纯药——021-50272975,76,77,78转 6220
规格:0.4UNITS
贮藏温度:-20C
Summary
This product is for research use only. Do not administer it to human.
Origin: Human muscle cell
Specific activity: 1.4 - 1.6 units/mg
Concentration: 1 units/mL
MW: approx. 36,000
Preparation: The enzyme is dissolved in 5 mM DTT,
50% glycerin and 50 mM Sodium phosphate buffer solution (pH 7.0).
Aldose Reductase is purified from the culture medium containing baculovirus-insect cell line
32d gene expression system. cDNA containing the entire protein coding region is expressed,
and the enzyme exhibits the same properties and characteristics of human muscle and retina.
Aldose Reductase catalyzes the reduction of glucose to sorbitol.
Sorbitol is subsequently converted to fructose by sorbitol dehydrogenase.
These two enzymes are key components of the polyol pathway,
the alternate route of glucose metabolism.   It is suggested that aldose reductase is
involved in the pathogenesis of diabetic complications and the inhibitors continue to
be developed at a vigorous pace.
[Reference]
Nishimura, C.   et al.: Biochim Biophys. Acta., 1078,
171 (1991).
  评论这张
 
阅读(393)| 评论(0)
推荐 转载

历史上的今天

在LOFTER的更多文章

评论

<#--最新日志,群博日志--> <#--推荐日志--> <#--引用记录--> <#--博主推荐--> <#--随机阅读--> <#--首页推荐--> <#--历史上的今天--> <#--被推荐日志--> <#--上一篇,下一篇--> <#-- 热度 --> <#-- 网易新闻广告 --> <#--右边模块结构--> <#--评论模块结构--> <#--引用模块结构--> <#--博主发起的投票-->
 
 
 
 
 
 
 
 
 
 
 
 
 
 

页脚

网易公司版权所有 ©1997-2017