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Jackson二抗授权|蛋白|细胞因子

西宝生物科研试剂团队服务糖,寡糖,多糖及检测服务和原料供应。Jackson二抗

 
 
 

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R&D Systems公司细胞生物学,提供优质的蛋白质,抗体,ELISA试剂盒,实验室试剂,细胞因子.包括Novus Biologicals, BiosPacific, Tocris Bioscience, Boston Biochem和Bionostics. Jackson二抗中国授权代理

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褪黑激素受体 黑素皮质素受体  

2010-11-17 12:58:46|  分类: 生物化学试剂 |  标签: |举报 |字号 订阅

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0877    Luzindole
Competitive melatonin MT1/MT2 antagonist
1034    4-P-PDOT
MT2 antagonist

0357    N-Acetyltryptamine             
Melatonin partial agonist (MT1/MT2). Also MT3 antagonist
0443    6-Chloromelatonin           10mg , 50mg
Chemical Name: N-[2-(6-Chloro-5-methoxyindol-3-yl)ethyl]acetamide
M.Wt:266.73
Formula:C13H15ClN2O2
Solubility:Soluble to 100 mM in DMSO
Purity: >99 %
Storage:Desiccate at +4°C
CAS No:[63762-74-3]
Potent melatonin agonist (pKi values are 9.10 and 9.77 for human recombinant MT1 and MT2receptors respectively). Displays higher affinity for binding to hamster brain membrane and chicken retina than melatonin.
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0737    2-Iodomelatonin
High affinity melatonin agonist
3550    Melatonin
Endogenous hormone; agonist at MT1 and MT2
1035    8-M-PDOT
Melatonin agonist
0680    2-Phenylmelatonin
Potent melatonin agonist

拮抗剂
1218    DH 97
MT2 receptor antagonist
0877    Luzindole
Competitive melatonin MT1/MT2 antagonist
1034    4-P-PDOT
MT2 antagonist
0623    Prazosin hydrochloride
MT3 antagonist, also α1 and α2B antagonist
Other
0896    GR 135531
High affinity melatonin MT3 ligand
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Melanocortin receptors are activated by members of the melanocortin family: α-, β- and γ-melanocyte stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). Endogenous antagonists include agouti and agouti-related protein (AgRP). The melanocortin receptors are G-protein-coupled and 5 subtypes exist, MC1-5. The melanocortins are involved in a wide range of physiological functions, including pigmentation, energy homeostasis, inflammation, immunomodulation, steroidogenesis and temperature control.


3492    ACTH (1-39)               1mg 
Adrenocorticotropichormone(1-39)
M.Wt:4541.1
Formula:C207H308N56O58S
Sequence:SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAE AFPLEF
CAS No:[12279-41-3]
Potent endogenous melanocortin receptor 2 (MC2) agonist (EC50 = 57 pM). Component of the hypothalamic-pituitary-adrenal (HPA) axis that stimulates glucocorticoid production and release from the adrenal cortex. Induces insulin resistance, promotes a proinflammatory profile and stimulates UCP-1 in adipocytes in vitro.
Potent endogenous MC2 agonist
2566    Melanotan II       1mg
别名:MT-II
分子式:C50H69N15O9
分子量:
1024.19
CAS No:[121062-08-6]
Sequence:
XDHFRWK

                 (Modifications: X = Nle & N-terminal Ac, Asp-2 = beta-Asp, Phe-4 = D-Phe, Lys-7 = epsilon-Lys, Cyclized = Asp-2 - Lys-7, C-terminal amide)

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High affinity melanocortin receptor agonist (Ki values are 0.67, 6.6, 34 and 46 nM for MC1, MC4, MC3and MC5 receptors respectively). Stimulates erectile activity, inhibits food intake and displays neuroprotective properties in vivo.
High affinity melanocortin receptor agonist
3424    γ1-MSH
Selective MC3 receptor agonist
2584    α-MSH
Endogenous melanocortin receptor agonist
3013    [Nle4,D-Phe7]-α-MSH
Melanocortin receptor agonist
3032    THIQ
Potent and selective MC4 receptor agonist

1831    HS 014
Selective MC4 receptor antagonist
1832    HS 024
Highly potent MC4 receptor antagonist
3426    JKC 363
Potent and selective MC4 receptor antagonist
3438    MCL 0020
Selective MC4 receptor antagonist

3476    Anti-MC2
Antibody recognizing MC2
3477    Anti-MC3
Antibody recognizing MC3
电话:13788991907   E-mail:电话@163.com提供
611    Lys-γ3-MSH
Pro-opiomelanocortin (POMC) derived peptide
1929    Melanocyte stimulating hormone release inhibiting factor
Inhibitor of α-MSH release; inhibits opioid effects in vivo
3420    SHU 9119
MC3 and MC4 antagonist, MC5 partial agonist
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