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R&D Systems公司细胞生物学,提供优质的蛋白质,抗体,ELISA试剂盒,实验室试剂,细胞因子.包括Novus Biologicals, BiosPacific, Tocris Bioscience, Boston Biochem和Bionostics. Jackson二抗中国授权代理

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伐地考昔Valdecoxib科研分析用及COX-2 inhibitor系列  

2010-11-22 13:07:00|  分类: NSAID系列 |  标签: |举报 |字号 订阅

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Valdecoxib                 5mg, 10mg, 25mg
伐地考昔,环氧化酶-2抑制剂
A prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis and it is classified as an NSAID
Cas No.  :       181695-72-7
伐地考昔Valdecoxib科研分析用 - Solomon - 标准品生化试剂毒素酶试剂盒
Formula Wt.:   314.36                                 
 Solubility :       Water 0.5 mg/ml    
电话:13788991907   E-mail:电话@163.com提供

COX-2 inhibitors belong to a class of anti-in?ammatory drugs (NSAID) that directly target cyclooxygenase-2 COX-2, an enzyme that is responsible for in?ammation and pain1,2. Unlike, regular NSAIDs, COX-2 inhibitors do not inhibit cyclooxygenase-1 (COX-1), an enzyme present in di?erent areas of the body, including the stomach. COX-1 produces prostaglandins that make natural mucus that protects the stomach. By blocking the activity of COX-1, NSAIDs cause stomach irritation, ulceration and bleeding.  The speci?city of COX-2 inhibitors makes them superior anti-in?ammatory drugs. Representative COX-2 inhibitors include rofe-coxib, valdecoxib, celecoxib, and lumiracoxib.COX-2 inhibitors have been also studied as cancer chemoprevention drugs due to their ability to preve in?ammation3,4,5.  Recently COX-2 inhibitors were investigated as chemopreventive agents for colorec cancer,6 prostate cancer3 and breast cancer7.

 Rofecoxib,罗非昔布       CAS:162011-90-7

Celecoxib(塞来昔布) CAS:169590-42-5

Lumiracoxib        100mg  ,250mg  ,1g      
伐地考昔Valdecoxib科研分析用及COX-2 inhibitor系列 - Solomon - 标准品生化试剂毒素酶试剂盒
 Is a Cox-2 selective inhibitor NSAID. A member of the arylalkanoic acid family of NSAIDs it binds to a separate site than the other Cox-2 inhibitors. Concerns that it may cause liver failure prompted withdraw from the market.
 
罗美昔布   ,化学名:2-[(2-氯-6-氟苯基)氨基]-5-甲基苯乙酸
Cas No.     220991-20-8
Formula Wt.     293.72




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