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Jackson二抗授权|蛋白|细胞因子

西宝生物科研试剂团队服务糖,寡糖,多糖及检测服务和原料供应。Jackson二抗

 
 
 

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R&D Systems公司细胞生物学,提供优质的蛋白质,抗体,ELISA试剂盒,实验室试剂,细胞因子.包括Novus Biologicals, BiosPacific, Tocris Bioscience, Boston Biochem和Bionostics. Jackson二抗中国授权代理

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TRPV1产品系列拮抗剂 Capsazepine  

2010-12-07 21:13:08|  分类: 生物化学试剂 |  标签: |举报 |字号 订阅

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Capsazepine                            
 Chemical Name: N-[2-(4-Chlorophenyl)ethyl]-1,3,4,5-tetrahydro-7,8-dihydroxy-2H-2-benzazepine-2-carbothioamide
TRPV1产品系列拮抗剂 Capsazepine - Solomon - 标准品生化试剂毒素酶试剂盒
分子量:376.9
分子式:C19H21 ClN2O2S
Solubility:Soluble to 25 mM in ethanol and to 100 mM in DMSO
Purity:>99 %
CAS No:[138977-28-3]
 10mg50mg
Selective vanilloid receptor antagonist (Ki = 3.2 μM). Inhibits carrageenan inflammation-induced hyperalgesic responses in the rat. Also activates amiloride-sensitive epithelial Na+ channel ENaCδ.
电话:13788991907   E-mail:电话@163.com 提供 TRPV1拮抗剂 capsazepine(辣椒素受体阻滞剂)
TRPV1(transient receptor potential vanilloid 1)是在机体广泛分布的非选择性阳离子通道,能被氢离子、高温以及其它内源性和外源性配体激活
(E)-Capsaicin            100mg 
Chemical Name: (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
分子量:305.42
分子式:C18H27NO3
Solubility:Soluble to 50 mM in DMSO and to 50 mM in ethanol
Purity :>98 %
CAS No :[404-86-4]
Prototypic vanilloid receptor agonist (pEC50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a subset of primary afferent sensory neurons, with subsequent antinociceptive and anti-inflammatory effects. Reversibly inhibits aggregation of platelets
    prototypic vanilloid receptor agonist


Olvanil              奥伐尼       10mg  ,50mg
Chemical Name: N-Vanillyloleoylamide
Potent vanilloid receptor agonist (pEC50 values are 8.1 and 7.7 at rat and human VR1 receptors respectively). Also blocks anandamide uptake (IC50 = 9 μM) and may bind to CB1 cannabinoid receptors. Antinociceptive following systemic administration
    potent vanilloid receptor agonist

Resiniferatoxin                1mg  
Chemical Name: 4-Hydroxy-3-methoxy-[(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR) -3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10
-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]benzeneacetate    
 Ultrapotent analog of capsaicin that is an agonist at vanilloid receptors (Ki = 43 pM). Like capsaicin, it acts as a selective modulator of primary afferent neurons.
M.Wt:628.72
Formula:C37H40O9
Solubility:Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:>98 %
CAS No:[57444-62-9]
    potent, selective, competitive TRPV1 antagonist

SB 366791             10mg  ,50mg

Chemical Name: 4'-Chloro-3-methoxycinnamanilide
Potent, selective and competitive vanilloid TRPV1 (VR1) receptor antagonist (pA2 = 7.71 at hVR1); antagonizes hTRPV1 receptors activated by agonists, noxious heat, but not protons. Displays selectivity over a wide range of receptors and systems including CB1 and CB2 receptors, voltage-gated Ca2+ channels and the hyperpolarization-activated current (Ih).
M.Wt:287.75
Formula:C16H14ClNO2
Solubility:Soluble to 10 mM in ethanol and to 100 mM in DMSO
Purity:>99 %
CAS No:[472981-92-3]
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