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Jackson二抗授权|蛋白|细胞因子

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R&D Systems公司细胞生物学,提供优质的蛋白质,抗体,ELISA试剂盒,实验室试剂,细胞因子.包括Novus Biologicals, BiosPacific, Tocris Bioscience, Boston Biochem和Bionostics. Jackson二抗中国授权代理

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GSK-1838705A 和ALK 抑制剂Crizotinib 科研分析用  

2016-02-15 12:00:06|  分类: 生物化学试剂 |  标签: |举报 |字号 订阅

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GSK-1838705A
1mg ,5mg,25mg

科研分析用 ,实验室专用, 联系电话 17717616967

Product ID     Product Name     Short Description      
A7400     ASP3026     ASP-3026 inhibits anaplastic lymphoma kinase (ALK)...     
A9600     AZD3463     AZD-3463 is an inhibitor of anaplastic lymphoma ki... 
C2900     CH5424802     CH5424802 is an inhibitor of anaplastic lymphoma k...   
C6935     Crizotinib     Crizotinib is an inhibitor of anaplastic lymphoma ...     
D4802     17-DMAG     17-DMAG is an inhibitor of HSP90 that exhibits neu...     
D5868     Doramapimod     Doramapimod is an anticancer chemotherapeutic inhi...    
G7540     GSK-1838705A     GSK-1838705A is an inhibitor of anaplastic lymphom...     
H1658     Heparin sodium     Heparin is an endogenous glycosaminoglycan that is...    
L1340     LDK378     LDK-378 is an anaplastic lymphoma kinase (ALK) inh...    
N8760     NVP-TAE684     NVP-TAE684 is an inhibitor of anaplastic lymphoma ...     
O7992     OTX-015     OTX-015 is an inhibitor of bromodomains (BRD) prot...     
Specifications
Cas No.
1116235-49-7
规格
1mg ,5mg,25mg
Product Name
GSK-1838705A
Synonym
GSK1838705A
Formula
C27H29FN8O3
Formula Wt.
532.57
Purity
≥98%
Store Temp
-20
References

GSK-1838705A is an inhibitor of anaplastic lymphoma kinase (ALK) and IGF-1R that exhibits anticancer chemotherapeutic activity. This compound inhibits cell and tumor growth in a variety of cancers, including non-small cell lung cancer (NSCLC), neuroblastoma, and large-cell lymphoma.

Crizotinib     ≥98%     25mg ,10mg ,100mg
ALK 抑制剂Crizotinib 科研分析用 ,实验室专用, 联系电话 17717616967

Crizotinib is an inhibitor of anaplastic lymphoma kinase (ALK), c-ros oncogene 1 (ROS1), and c-Met, binding competitively to the ATP-binding pocket of kinases. Crizotinib exhibits anticancer chemotherapeutic benefit in the treatment of non-small cell lung cancer (NSCLC) and is currently in clinical trials as a potential treatment for neuroblastoma and other advanced solid tumors. In cellular models, this compound upregulates pro-apoptotic BIM and downregulates anti-apoptotic survivin to induce apoptosis and inhibit cell proliferation.

Cas No.
877399-52-5
Product ID
C6935
Product Name
Crizotinib
Formula
C21H22Cl2FN5O
Formula Wt.
450.34
Purity
≥98%
References
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